Vol. 2 No. 1 (2026): May, 2026

Articles

• Evaluation of the Potential of Self-Nanoemulsifying Drug Delivery System (SNEDDS) in Increasing Oral Bioavailability of Low-Solubility Drugs

  Muhammad Nurul Fadel, Emma Jayanti Besan, Dzukharian Munandar, Husnunnisa, Cut Intan Annisa Puteri

  Pages 45-59 DOI 10.69855/farmasi.v2i1.544 Published 2026-05-05

  Losartan potassium, a Biopharmaceutics Classification System (BCS) Class II drug, exhibits poor aqueous solubility and limited oral bioavailability. This study aimed to develop and optimize a Self-Nanoemulsifying Drug Delivery System (SNEDDS) to enhance...

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• Development of Rapid Dispersible Tablet Preparations Using Synthetic and Natural Superdisintegrant Disintegrants: Comparative Performance Analysis

  putri tri hartini, pertiwi awilda, Ratna mildawati, Khazanah Nurain Nurdin, Dara Sukma Ratmelya

  Pages 30-44 Published 2026-05-04

  Rapid dispersible tablets (RDTs) are patient-friendly oral dosage forms designed to disintegrate rapidly in the oral cavity or in the presence of a small amount of water, thereby improving patient compliance, particularly among pediatric, geriatric, and...

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• Optimization and Stability Testing of a Nanostructured Lipid Carrier (NLC)-Based Emulgel System for Transdermal Delivery of Anti-Inflammatory Drugs

  Muhammad Nurul Fadel, Emma Jayanti Besan, Dzukharian Munandar, Zola Efa Harnis, Indri Dwi Rahasasti

  Pages 1-14 DOI 10.69855/farmasi.v2i1.522 Published 2026-05-02

  Nanostructured Lipid Carriers (NLC) are second-generation lipid nanoparticles composed of solid and liquid lipids that improve drug loading, stability, and controlled release. Incorporating NLC into an emulgel enhances transdermal drug delivery by...

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• Formulation and Characterization of PEGylated Liposomes as a Targeted Delivery System for the Chemotherapy Drug Doxorubicin

  putri tri hartini, Arbayah, Ziza Putri Aisyia Fauzi, Fendy Prasetyawa, Revan Busriano Putra

  Pages 60-76 DOI 10.69855/farmasi.v2i1.526 Published 2026-05-15

  Doxorubicin (DOX) is an effective anticancer agent, but its clinical use is limited by severe systemic toxicity. This study developed and optimized PEGylated liposomes containing DOX to improve therapeutic efficacy and safety. Liposomes were prepared...

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• Formulation Study and Evaluation of the Effectiveness of Natural Polymer-Based Dissolving Microneedles for Model Vaccine Delivery

  Emma Jayanti Besan, Muhammad Nurul Fadel, Nur Masyithah Zamruddin, Dara Sukma Ratmelya, Yuneka Saristiana

  Pages 15-29 Published 2026-05-03

  Dissolving microneedle (DMN) arrays made from biocompatible natural polymers offer a promising transdermal vaccine delivery system that can reduce pain, eliminate cold-chain dependence, and minimize the need for trained healthcare workers compared to...

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  27 views 14 downloads