Differences in Ferritin Levels and Menstrual Disorders between Vegetarian and Non-Vegetarian Women in Denpasar

Authors

  • Fatinah Shahab Universitas Wahid Hasyim Semarang

DOI:

https://doi.org/10.69855/mgj.v2i3.183

Keywords:

Ferritin, Menstrual Disorders, Vegetarian, Women of Childbearing Age, Iron

Abstract

Iron deficiency is a significant nutritional challenge for women of reproductive age, especially those who follow a vegetarian diet. Ferritin, as a key indicator of iron reserves, plays an important role in diagnosing latent iron deficiency, which can negatively affect reproductive health, including causing menstrual disorders. This study compares ferritin levels and the incidence of menstrual disorders between 50 vegetarian and 50 non-vegetarian women aged 18–45 years in Denpasar City. Ferritin levels were measured using the ELISA method, while data on menstrual disorders were collected through the Menstrual Symptom Questionnaire (MSQ). The data were analyzed using independent t-tests, chi-square tests, and multivariate logistic regression (α=0.05). The study found that the average ferritin level in vegetarian women (21.4 µg/L) was significantly lower than in non-vegetarian women (36.9 µg/L; p<0.001), and the prevalence of menstrual disorders such as dysmenorrhea and irregular cycles was higher among vegetarians. Logistic regression analysis confirmed that a vegetarian diet (odds ratio [OR]=2.98; p=0.014) and ferritin levels below 30 µg/L (OR=3.62; p=0.007) were significant predictors of menstrual disorders. Thus, a vegetarian diet and low ferritin levels are identified as key risk factors for menstrual disorders in women of reproductive age. These findings underscore the importance of monitoring ferritin status and applying appropriate nutritional strategies for vegetarian women to help support optimal reproductive health.

References

Arisanti, N. K. R., Ariati, N. N., & Gumala, N. M. Y. (2023). Relationship between protein, iron, and vitamin C intake levels and menstrual cycle in adolescents at Sai Study Group Denpasar. Journal of Nutrition Science, 12(2), 138–146. https://doi.org/10.33992/jig.v12i2.2132

Bakir, S., Shamoon, R., & Polus, R. (2025). Serum levels of ferritin and vitamin B12 in a cohort of healthy non-anemic female medical students. Advanced Medical Journal, 10(1), 50–58. https://doi.org/10.56056/amj.2025.317

Bhartiya, J. P., Chaudhary, V., Singh, A., & Kathariya, G. (2022). Estimation of ferritin in vegetarian and non-vegetarian female medical college students. Asian Journal of Pharmaceutical and Clinical Research, 15(3), 2022. https://doi.org/10.22159/ajpcr.2022v15i3.44074

Firdous, S., Rama Devi, M., & Ambareesha, K. (2023). Estimation of serum iron and serum ferritin among women in reproductive age group. International Journal of Academic Medicine and Pharmacy, 5(4). https://doi.org/10.47009/jamp.2023.5.4.91

Gallego-Narbón, A., Zapatera, B., & Vaquero, M. P. (2019). Physiological and dietary determinants of iron status in Spanish vegetarians. Nutrients, 11(8), 1734. https://doi.org/10.3390/nu11081734

Ghazzay, H., Jasim, M. A., Shukur, A. S., Altaha, M., & Ibrahim, S. (2021). Low ferritin with normal hemoglobin, a common neglected and hidden hematological disorder. Annals of Tropical Medicine and Public Health, 24. https://api.semanticscholar.org/CorpusID:235854092

Ghosh, S., K Roopashree, Ragothaman, P., & Vashishtha, S. (2022). Determination of severity of premenstrual syndrome among vegetarian and non-vegetarian women. National Journal of Physiology, Pharmacy and Pharmacology, 1–1. https://doi.org/10.5455/njppp.2023.13.10506202229112022

Gomes, F., Teles, R. S., Domingues, K., et al. (2021). Iron deficiency in vegetarian and omnivorous individuals: Analysis of 1340 individuals. Nutrients, 13(9), 2964. https://doi.org/10.3390/nu13092964

Haider, L. M., Schwingshackl, L., Hoffmann, G., & Ekmekcioglu, C. (2018). The effect of vegetarian diets on iron status in adults: A systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition, 58(8), 1359–1374. https://doi.org/10.1080/10408398.2016.1259210

Pawlak, R., Berger, J., & Hines, I. (2016). Iron status of vegetarian adults: A review of literature. American Journal of Lifestyle Medicine, 12(6), 486–498. https://doi.org/10.1177/1559827616682933

Putri Dewi, N. L. P., & Ariantari, N. P. (2023). The potential of red clover phytoestrogen as a nutraceutical to address menopause syndrome. Proceedings of the Workshop and National Seminar on Pharmacy, 2, 289–309. https://doi.org/10.24843/wsnf.2022.v02.p24

Rahmawati, F. C. (2023). Relationship between iron intake and age of menarche with dysmenorrhea incidence in adolescent girls. Journal of Innovative Research, 2(3), 469–476. https://doi.org/10.54082/jupin.105

Slywitch, E., Savalli, C., Duarte, A. C. G., & Escrivão, M. A. M. S. (2021). Iron deficiency in vegetarian and omnivorous individuals: Analysis of 1340 individuals. Nutrients, 13(9), 2964. https://doi.org/10.3390/nu13092964

Takeda, R., Kuriyama, Y., & Yoshida, Y. (2024). Restorative effect of bean ferritin iron on low hemoglobin level in premenopausal women with menstruation-induced anemia: A randomized, double-blind placebo-controlled intergroup trial. Functional Foods in Health and Disease, 14(3), 169–183. https://doi.org/10.31989/ffhd.v14i3.1331

Vaquero, M. P., García-Maldonado, E., Gallego-Narbón, A., Zapatera, B., Alcorta, A., & Martínez-Suárez, M. (2024). Iron deficiency is associated with elevated parathormone levels, low vitamin D status, and risk of bone loss in omnivores and plant-based diet consumers. International Journal of Molecular Sciences, 25(19), 10290. https://doi.org/10.3390/ijms251910290

Downloads

Published

2025-08-28

How to Cite

Fatinah Shahab. (2025). Differences in Ferritin Levels and Menstrual Disorders between Vegetarian and Non-Vegetarian Women in Denpasar. Miracle Get Journal, 2(3), 90–100. https://doi.org/10.69855/mgj.v2i3.183